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Tapal ER 100mg

$ 180.00$ 520.00

In Stock

Available Options

pack sizePriceQuantity 
100 Tablets$ 180.00
200 Tablets$ 300.00
300 Tablets$ 420.00
400 Tablets$ 520.00

Quick Overview

Brand Name: Tapal 100 (Extended Release)
Generic Name: Opioid Painkiller
Active Ingredient: Tapentadol
Manufacturer: MSN Laboratories
Drug Class: Opioid Analgesic
Strength: 100 mg
Packaging: 10 Tablet in 1 Strip
Treatment: Moderate to severe Chronic pain (Diabetic Neuropathy and Trigeminal Neuralgia)
Time Duration: Time to work 30 to 60 minutes
Price: $180 to $520

Product Description

What is Tapal ER 100mg?

Tapal ER 100 mg (Extended Release) moderate to severe chronic pain reliever tablet used to treat Diabetic neuropathy pain and Trigeminal Neuralgia. Tapentadol is active component in tapal 100mg (ER) tablet.

Tapal ER 100mg  Opioid tablet is prescribed for long-term pain when other non-opioid painkillers do not treat pain effectively.

What is the use of Tapal 100mg ER Tablet?

Tapal 100 mg (Extended Release) tablet is used to treat moderate to severe chronic pain (long-term) conditions such as Back Pain, joint pain, serious foot problems, migraine, and Diabetic neuropathy.

Tapal ER 100 mg is mostly Prescribed for Diabetic Neuropathy (long-term) Pain treatment.

What is Diabetic Neuropathy?

Diabetic neuropathy is the most common long-term pain caused by diabetic mellitus (DM). It most usually develops as distal sensorimotor neuropathy, in which decreased or nonexistent protective feeling in the lower limbs increases the risk of foot ulcers and peripheral neuropathic pain.

Diabetic Neuropathy pain is defined by tingling, burning, sharp, shooting, and lancinating sensations, as well as electric shock sensations. It is normally classified as moderate to severe, and it is often worse at night, causing problems with sleep.

The pain might be chronic and accompanied by cutaneous allodynia, which can have a significant impact on the patient’s quality of life, limiting their capacity to do everyday tasks and having a negative impact on their mood. Pain may also be a cause of withdrawal from recreational and social activities, and it may be related to depression.

Diabetic neuropathy, which impacts over 90% of diabetic patients, is a common sign of both type 1 and type 2 diabetes. Although pain is one of the most common symptoms of diabetic neuropathy, the pathophysiological mechanisms underlying it are yet unknown. Although it is well known that hyperglycemia’s harmful effects play an essential role in the development of this problem, various additional ideas have been suggested.

What causes Diabetic Neuropathy?

Diabetes neuropathy is characterized by high blood sugar levels that are sustained over time.

Other variables that can induce nerve damage include:

  • Damage to blood vessels caused by excessive cholesterol levels
  • Mechanical injuries such as carpal tunnel syndrome
  • Lifestyle factors such as smoking and alcohol consumption

Low vitamin B12 levels can potentially cause neuropathy. Metformin, a commonly used diabetes treatment, can lower vitamin B12 levels. You can request a simple blood test from your doctor to determine any vitamin problems.

Symptoms of Diabetic Neuropathy:

  • Numbness or less ability to feel pain or temperature changes
  • Tingling or burning feeling
  • Sharp pains or cramps
  • Muscle weakness
  • Some people are so sensitive to touch that, even a bedsheet’s weight can be painful
  • Serious foot problems, such as ulcers, infections, and bone and joint damage

How Does Tapal ER 100mg Treat Chronic Diabetic Neuropathy Pain?

Tapal ER 100mg Extended-release (ER) tablet works directly on opioid receptors in the central nervous system and reduces By interacting with the way nerves link pain between the brain and the body, pain can be reduced.

Tapentadol ER for oral administration was approved by the FDA in 2011 for the relief of moderate to severe chronic pain and later to address diabetic neuropathy, which necessitates continuous administration of the drug for a prolonged period.

Tapentadol is classified as a Schedule II substance by the US Drug Enforcement Administration. Additionally, it has obtained European approval for the treatment of severe chronic pain in individuals who are unable to obtain adequate analgesia without narcotics.

What is the best way to take Tapal ER tablets?

Swallow the Tapal ER 100mg Tablet in one go with plenty of water as directed by the physician. Take Tapal ER 100 mg Tablet at the time as directed by your doctor. Swallow it all at once with plenty of water. You can take this tablet with or without food. The doctor will work out your dosage after observing your condition.

Side Effects:

  • Nausea
  • Constipation
  • Dizziness
  • Headache
  • Somnolence
  • Vomiting


  • Tapal ER 100mg is contraindicated in patients with significant respiratory depression.
  • Tapal Extended Release is contraindicated in patients with acute or severe bronchial asthma or hypercarbia in an uncontrolled setting or the absence of resuscitation equipment.
  • It is contraindicated in patients with known or suspected paralytic ileus.
  • Tapal ER 100mg is contraindicated in patients with hypersensitivity (eg, anaphylaxis, angioedema) to tapentadol or any of the other ingredients of the product.
  • It is contraindicated in patients receiving monoamine oxidase inhibitors (MAOIs) or who have taken them in the past 14 days due to potential additive effects on norepinephrine levels that may result in adverse cardiovascular events.

Precautions and Warnings:

Before using Tapal ER 100 mg tablet, patients were at risk of opioid abuse or addiction. Patients with a personal or family history of using drugs (including drug or alcohol abuse or addiction) or mental illness (e.g., serious depression) are at a higher risk of opioid abuse.  Patients at high risk can still be treated well with modified-release opioid formulations; however, these patients will need to be closely monitored for indications of misuse, abuse, or addiction. Monitor all patients taking opioids for signs of overuse, abuse, and addiction regularly, because these medicines can lead to addiction even when used properly.

Misuse or misuse of Tapal ER 100mg by crushing, chewing, snorting, or injecting the dissolved product results in uncontrolled opioid administration and poses a considerable risk of overdose and death.

The most serious side effect of opioid agonists, including tapal 100 ER, is respiratory depression. Respiratory depression, if not recognized and treated promptly, can result in respiratory arrest and death. Opioid-induced respiratory depression is characterized by a decreased need to breathe and a slower rate of respiration, which is frequently accompanied by a “sighing” pattern of breathing (deep breaths separated by excessively long pauses).

Tapal ER should be dosed and adjusted correctly to reduce the risk of respiratory depression. When converting patients from another opioid product, missing the Tapal 100 mg (ER) dose can result in a lethal overdose with the first dose.

Tapentadol intake by accident, particularly in minors, can result in a deadly overdose.

Tapal ER should not be used in patients who have severe renal impairment due to the accumulation of a metabolite generated by the glucuronidation of tapentadol. The elevated metabolite’s clinical significance is unknown.

Missed Dose

If you miss a dosage of this medication, skip it and resume your regular dosing timeline. Do not take two doses.


Tapentadol is a central nervous system depressant, it can slow a person’s heart rate as well as their breathing. Typically, symptoms of a potential Tapentadol overdose are extreme drowsiness, sweating, confusion, blurred vision, clammy skin, slowed breathing, and muscle weakness.


  • Keep out of children’s reach.
  • Do not keep expired or no-longer-needed medications.
  • Inquire with your healthcare provider about how to properly dispose of any medications you no longer require.
  • Store the medication at room temperature in a well-secured container away from heat, moisture, and direct light. Prevent freezing.
  • After opening, keep the oral liquid bottle upright.


MSN Laboratories, founded in 2003, manufactures Tapal ER 100mg Tablet. It is widely regarded as a reliable manufacturer and supplier of pharmaceutical drugs.

MSN Laboratories Pvt. Ltd creates medications that adhere to industry standards and use high-quality components. Skilled specialists monitor these medicines during the production process to ensure quality.

Frequently Asked Questions:

Q1) Tapal 100 mg (Extended Release): What is it and why is it recommended?

Ans: Tapal ER 100mg is an Extended-release Tablet that contains Tapentadol an opioid medicine. It is used to treat severe chronic pain in patients who are unable to be treated with another painkiller drug.

Q2) Can I take Tapal Extended-Release Tablets if I’m pregnant?

Ans: When Tapal 100 mg extended-release tablet is used during pregnancy, it may produce a number of adverse effects. Consult your doctor before taking any medicine while pregnant.

Q3) Can I use Tapal ER Tablets during breastfeeding?

Ans: Tapal ER Tablets should be taken only after consulting with a doctor if you are nursing.

Q4) Does Tapal ER100 mg impact my ability to drive?

Ans: Do not drive or operate machinery if you feel tired, dizzy, have blurred vision, or have difficulties concentrating after taking the Tapal extended-release tablet. You may resume your activities whenever you feel normal again. Consult with your doctor.

Q5) Is Tapal ER 100mg an addictive medication?

Ans: Tapal 100mg (ER) has the potential to cause psychological as well as physical dependence. Tapal ER 100mg should only be used for short periods if you tend to become addicted to drugs or are dependent on them. You must first consult with your doctor to discuss your options.

Q6) Is it safe for me to drive after taking Tapal ER Tablets?

Ans: No, It might make you dizzy and impair your ability to drive.

Q7) Can I consume alcohol while on Tapal ER Tablets?

Ans: No, When Tapal ER Tablet is used with alcohol, it might produce severe dizziness.

Additional information

pack size

100 Tablets, 200 Tablets, 300 Tablets, 400 Tablets


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