Semaglutide 2.4 mg Injection

Product Description

Overview of Semaglutide 2.4 mg injection

Introduction:

Semaglutide 2.4 mg injection is used to treat type 2 diabetes and obesity. Glucagon-like peptide-1 (GLP-1) receptor agonists mimic GLP-1 activity. This medication controls blood sugar levels by increasing insulin secretion, lowering glucagon, and slowing stomach emptying. Semaglutide 2.4 mg, taken once a week, helps diabetics lose weight and control their blood sugar.

Chemical Composition and Structure:

Semaglutide is a synthetic version of the GLP-1 hormone. Its chemical composition consists of a 31-amino acid peptide chain with particular modifications to improve stability and potency. The chemical formula is C187H291N45O59, with a molecular weight of around 4113.6 g/mol.

Discovery and Initial Research:

Semaglutide was originally developed to help people with type 2 diabetes manage their disease. Scientists discovered that Semaglutide, which mimics a hormone called glucagon-like peptide-1 (GLP-1), could enhance blood sugar control in diabetes patients

What is Semaglutide?

Semaglutide is regarded as a “miracle drug” for type 2 diabetes and weight loss, acting as both an antidiabetic and an anti-obesity treatment for long-term weight management. Semaglutide is a glucagon-like peptide-1 receptor agonist. It has two administration options: subcutaneously and orally. It is marketed under the names Ozempic and Rybelsus for diabetes and Wegovy for weight loss. Discover Semaglutide for type 2 diabetes and start managing your health now.

Semaglutide is not indicated to treat type 1 diabetes or diabetic ketoacidosis in patients. Semaglutide is intended for chronic weight management in people who are obese or overweight and have at least one weight-related disorder (such as high blood pressure, type 2 diabetes, or high cholesterol). It should be used in conjunction with a low-calorie diet and increased exercise. Semaglutide is also approved for chronic weight management in pediatric patients aged 12 and above who have an initial BMI of the 95th percentile or greater for age and sex.

Semaglutide Generic Name: Semaglutide is not available as a generic medication. Novo Nordisk manufactures three different brands of semaglutide (Wegovy, Ozempic, and Rybelus) that are FDA-approved for a variety of diseases.

Semaglutide Drug Class: Semaglutide belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. It mimics the GLP-1 hormone, released in the gastrointestinal tract in response to eating. GLP-1 helps the body create more insulin, which lowers blood glucose (sugar).

What is a Fitaro 2.4 mg injection?

Fitaro Semaglutide Injection 2.4 mg, produced by Incepta Pharmaceuticals Ltd., includes the generic medication semaglutide. It is a GLP-1 receptor agonist that is used to control weight and treat type 2 diabetes. The drug’s chemical makeup is intended to provide long-term efficacy by aiding in blood sugar regulation and appetite control.

Brand names:

Fitaro: The brand name under which Incepta Pharmaceuticals Ltd. sells semaglutide.

Other common brand names for semaglutide are:

Ozempic: Ozempic is primarily used for the treatment of type 2 diabetes and off-label used as weight loss.

Wegovy: Wegovy is approved for weight management.

Rybelsus: Rybelsus is used to treat type 2 diabetes mellitus.

How does Semaglutide 2.4 mg Injection work?

Semaglutide 2.4 mg Injection operates primarily through semaglutide, a GLP-1 receptor agonist. Here’s how it works.

GLP-1 Receptor Agonist:

Semaglutide acts as a GLP-1 receptor agonist, mimicking the action of the body’s endogenous hormone GLP-1.

Mechanism of action:

Enhances Insulin Release: It increases insulin secretion from pancreatic beta cells in response to high blood glucose levels. This helps to reduce blood sugar levels after meals.

Inhibits Glucagon Release: Semaglutide inhibits the release of glucagon, a hormone that typically raises blood glucose levels. This activity contributes to improved blood sugar regulation.

Slows Gastric Emptying: By delaying the emptying of stomach contents into the small intestine, semaglutide helps to modulate the rate of nutritional absorption into the bloodstream. This may lead to a more gradual and consistent rise in blood glucose levels following meals.

Increases Satiety: Semaglutide acts on the brain to increase a sense of fullness (satiety), which can lead to lower food intake and aid weight reduction attempts.

Effects of Blood Sugar and Weight:

Blood Sugar Regulation: By increasing insulin production, reducing glucagon release, and decreasing stomach emptying, semaglutide helps to stabilize blood sugar levels in patients with type 2 diabetes.

Weight Management: Semaglutide’s satiety-inducing effect, combined with its ability to prolong stomach emptying, can result in lower calorie intake and steady weight loss over time. Semaglutide has been demonstrated in clinical trials to significantly reduce weight in patients.

Overall Impact:

Fitaro Semaglutide 2.4 mg Injection are used to improve glycemic control in type 2 diabetic patients and to aid in weight management.

Its mode of action contributes to addressing both the metabolic features of diabetes (blood sugar regulation) and the difficulties of obesity (appetite control and weight loss).

How to give yourself Semaglutide 2.4 mg injection

To self-administer Semaglutide 2.4 mg injection, wash your hands thoroughly and wipe the injection site with an alcohol swab. Attach a new needle to the semaglutide pen, remove the caps, and set the dose to 2.4 mg.

To start the injection, press hard against your skin. Press the pen firmly against your skin throughout the injection, which should take about 10 seconds. Before you replace the pen cap, remove the needle and store it in a sharps container. Store the pen as directed, typically in the refrigerator. Follow your doctor’s recommendations and rotate injection sites to avoid irritation.

Semaglutide 2.4mg Dosage:

Fitaro (semaglutide) is commonly given for weight loss at a dose of 2.4 mg injection once per week for both type 2 diabetes and weight management. This dosage has been examined and proven to be beneficial in assisting persons in losing considerable amounts of weight. It replicates the action of the GLP-1 hormone, which aids in appetite suppression, generating a sense of fullness, and eventually contributing to weight loss.

It’s worth noting that Fitaro semaglutide 2.4mg for weight loss is typically taken in conjunction with diet and exercise. The medicine helps to manage cravings and lower caloric intake, which contributes to its efficacy in aiding weight loss attempts.

Dose Escalation Schedule:

• Week 1- 4: Semaglutide 0.25 mg injection (10 units)
• Week 5 – 8: Semaglutide 0.5 mg injection (20 units)
• Week 9 -12: Semaglutide 1 mg injection (40 units)
• Week 13 – 16: Semaglutide 1.7 mg injection (68 units)
• Week 17 and onwards: Semaglutide 2.4 mg injection (96 units)

Explore how semaglutide dosages can help with your weight loss goal. Click here to learn more about semaglutide dosing schedules.

Pros and Cons of semaglutide 2.4mg for weight loss:

Pros:

1. Effective Weight Loss: The biggest benefit of Semaglutide 2.4mg is weight loss. One injection per week is enough to leave you feeling full and satisfied, which leads to fewer cravings, fewer calories, and effective weight loss. Some patients lost 15% of their body weight using Semaglutide in clinical trials.
2. Improved Metabolic Health: Semaglutide not only promotes weight loss, but it also improves overall metabolic health by lowering the risk of cardiovascular disease and improving glycemic management.
3. Reduces Appetite: Semaglutide helps manage hunger by replicating the actions of GLP-1, a natural hormone that regulates appetite.
4. Improves blood sugar: Stabilizing your blood sugar means having fewer cravings and eating fewer calories. Finally, this helps you lose weight and keep it off. Furthermore, managing blood sugar helps to lower the risk of cardiovascular events such as strokes and heart attacks.
5. Cardiovascular Benefits: Lowers the risk of cardiovascular events like heart attacks and strokes.

Cons:

1. Injection Administration: Semaglutide 2.4 mg injection is usually provided as a once a week. Some people who are uncomfortable with injections may be put off by this method of delivery./ which may be inconvenient for some individuals.
2. Cost: Semaglutide is expensive, and insurance coverage varies. For individuals who require coverage, the cost may be a considerable disadvantage.
3. Side Effects: Semaglutide’s most common side effects are nausea, diarrhea, and constipation. While these side effects usually resolve with time as the body adjusts to the medicine, they can be troublesome for some people.
4. Injection Site Reactions: Pain, redness, and swelling may occur at the injection site.
5. Serious Health Risks: Rare but serious risks include pancreatitis, gallbladder illness, and kidney difficulties.

Precautions of semaglutide 2.4 mg injection:

Pancreatitis: If pancreatitis is suspected, quit semaglutide immediately, and do not restart if pancreatitis is confirmed.

Acute Gallbladder Disease: If cholelithiasis is suspected, gallbladder tests and clinical monitoring are recommended.

Hypoglycemia: Concomitant usage of insulin secretagogues or insulin may raise the risk of hypoglycemia. It may be essential to reduce insulin secretagogue or insulin doses.

Diabetic Retinopathy: Patients who have diabetic retinopathy should be monitored.

Heart Rate: The heart rate should be checked at regular intervals.

Suicidal behavior and ideation: Monitor for depression or suicidal thoughts. If symptoms occur, semaglutide should be withdrawn.

Allergies: Tell your doctor if you are allergic to semaglutide or any other drugs.

Pregnancy and Breastfeeding: If you are pregnant, plan to become pregnant, or are breastfeeding, you should contact your healthcare professional.

FAQS:

Q1) How many units of semaglutide is 2.4 mg ?

Ans: You will begin taking semaglutide at a weekly dose of 0.25 mg (10 units) and gradually increase the dosage every 4 weeks until you reach the full dose of 2.4 mg (96 units).

Q2) Is Semaglutide 2.4 mg Injection appropriate for type 1 diabetes?

Ans: Semaglutide 2.4 mg Injection cannot treat type 1 diabetes. It is approved and recommended for type 2 diabetes and obesity control in adults. Fitaro improves insulin secretion and sensitivity, which require some insulin synthesis, in type 1 diabetes. Type 1 diabetics need insulin replacement therapy and additional therapies to manage their disease. Diabetics must follow their doctor’s treatment recommendations based on their health needs.

Q3) What happens if you don’t eat while on semaglutide?

Ans: If you don’t eat while taking semaglutide, you may notice a decrease in appetite, but insufficient intake can also cause weariness, malaise, or dizziness, among other more serious conditions such as malnutrition. Semaglutide also reduces the rate of stomach emptying, so we must account for this as well.

Additional information